NR4A1 and breast carcinoma: Luminal A subtype, like the MCF-7 cell line, is the most frequent breast cancer subtype that is low grade, tends to grow slowly and has the highest survival rate, whereas triple-negative, similar to MDA-MB-468, is less common breast cancer subtype, has the lowest survival rate, has very high aggressive potentials and is difficult to treat because no hormone receptor has been found to target yet.