USF2 and lung adenocarcinoma: In lung adenocarcinoma cells, FIP from Ganoderma microsporum (FIP-gmi) activates autophagy to inhibit cancer cell growth [17]; furthermore, FIP-gts induces premature senescence [18], whereas FIP-SN15 [19], FIP-glu [20], and FIP-sch2 promote apoptosis [16].