Mutations in APOE [86], signal transducing adaptor family member 1 (STAP1) [87], lysosomal acid lipase (LIPA) [47], ABCG5 or ABCG8 [88] genes can also generate a FH like phenotype, but its frequency is very low in all of the cases. Here, LIPA is linked to familial hyperaldosteronism.