This suggests that, during diet-induced recovery from NASH, some inflammatory features persist, while BPF reduces inflammation by acting on Il6 and Il10. In fact, we found increased numbers of immune effector cells, mainly Kupffer and some lymphocytes, infiltrating CAF/SC livers while much fewer immune cells in CAF/SC+BPF at week 10 of dietary intervention supplemented with bergamot polyphenols. The gene discussed is IL6; the disease is metabolic dysfunction-associated steatohepatitis.