ROBO1 and adenomyosis: In comparison to the normal endometrium, Nie and colleagues demonstrated that SLIT expression was higher in the ectopic endometrium of women with adenomyosis, while ROBO1 immunoreactivity and MVD were higher in both eutopic and ectopic endometria of women with adenomyosis and that these biomarkers positively correlated with the severity of dysmenorrhea [61].