Relative G0S2 expression was higher in GBM than in lower grade gliomas (7.57 vs. 3.59, p = 1269e-16), and was higher in WHO grade III glioma than in WHO grade II glioma (3.12 vs. 2.49, p = 0.006330) among the lower grade gliomas (Fig 1A). Here, G0S2 is linked to central nervous system cancer.