Findings from the Df16A± mouse model of schizophrenia demonstrate impaired social behavior, decreased number of parvalbumin-expressing interneurons in CA2, decreased activity of CA2 pyramidal neurons (Piskorowski et al., 2016), and decreased synchrony between hippocampus and PFC (Sigurdsson et al., 2010). This evidence concerns the gene PVALB and schizophrenia.