When compared to healthy volunteers group, in I stage of cancer only VEGF-C, in II – VEGF-A, VEGF-C, VEGF-D and CA 15–3, in stage III – VEGF-A and CA 15–3, in stage IV – VEGF-A, VEGF-C and CA 15–3, showed statistical significance (in all cases p < 0.05). This evidence concerns the gene VEGFA and cancer.