Due to the fact that angiogenesis and lymphangiogenesis are very important processes involved in the development of tumor changes and enable not only the creation of metastases, but also determine the local development of cancer [7], we predict that new candidates for tumor markers may be VEGF family members such as: VEGF-A, VEGF-C, VEGF-D and their receptor – VEGFR-2. This evidence concerns the gene KDR and cancer.