IFNG and Hepatitis: In agreement with previous findings that iNKT cells and IFNγ play important roles in the development of Con-A induced hepatitis (19, 20), exacerbated hepatocyte necrosis (Figure 1E) and increased alanine aminotransferase (ALT) as well as aspartate aminotransferase (AST; Figure 1F) were detected in MPTP treated mice after Con-A injection.