Some studies also found that inhibiting the function of MIF could significantly reduce the growth of cancer in vitro or in vivo systems, such as bladder cancer, lung cancer, and colon cancer (Choudhary et al., 2013; Kindt et al., 2013; Ioannou et al., 2014; Mawhinney et al., 2014; Varinelli et al., 2015). The gene discussed is MIF; the disease is cancer.