CSF1R and multiple sclerosis: CSF1R inhibition reduces neuroinflammation leading to improved disease phenotype in several mouse models of neurodegenerative diseases including Alzheimer’s disease and multiple sclerosis (Dagher et al., 2015; Wieghofer et al., 2015; Beckmann et al., 2018; Sosna et al., 2018; Spiller et al., 2018).