TRPV1 and ocular hypertension: We investigated whether TRPV1 and 4 channels might be expressed in SMI-32 cells, which label αRGCs, large-diameter monostratified cells that arborize in ON or OFF sublaminae of the inner plexiform layer (Coombs et al., 2006), play a role in contrast sensitivity and are sensitive to ocular hypertension (Della Santina et al., 2013; Schmidt et al., 2014; Ou et al., 2016).