Moreover, Kindlin-2 exerted a significant impact on worse prognosis of PDAC (DFS/RFS/PFS), ESCC (OS, DFS/RFS/PFS), HCC (OS), ccRCC (OS), BC (OS, DFS/RFS/PFS), CHS (OS), OSS (OS), GC (DFS/RFS/PFS) and glioma (OS), but not of PDAC (OS), GC (OS), sEOC (OS, DFS/RFS/PFS). The gene discussed is FERMT2; the disease is glioma.