Expression of FAM174B, MAD1L1, SCARB1, MFSD12, SEMA6A, SLC45A2, and TBC1D16 was found to be upregulated and associated with worse OS in melanoma patients, while only MFSD12 and SLC45A2 were associated with worse DFS for melanoma patients (Fig. 1e, f). This evidence concerns the gene SEMA6A and melanoma.