Fig. S2A) and atherosclerosis (Fig. 4A) signalling pathways our results showed upregulated expression of low-density lipoprotein (Ldl), high-density lipoprotein (Hdl), ATP binding cassette subfamily A member 1 (Abca1), ATP binding cassette subfamily G member 1 (Abcg1), Abcg4, interleukin 1 alpha (Il-1), E-selectin ligand-1 (Esl-1) and downregulated expression of phospholipase A2 (Pla-2). The gene discussed is IL1A; the disease is atherosclerosis.