DHODH and malaria: Examples in the Medicines for Malaria Venture (MMV) pipeline of compounds having both blood and liver stage activity [1] include: the DHODH (dihydroorotate dehydrogenase) inhibitor DSM265 [26, 27], the PI-4 kinase inhibitor MMV048 (MMV390048; [28]) and the EF2 (Elongation Factor 2) inhibitor DDD498 (DDD107498; [29]), now also known as M5717.