The family of neurodegenerative brain iron accumulation (NBIA) disorders includes Pantothenate kinase-associated neurodegeneration (PKAN), Aceruloplasminemia, beta-propeller protein-associated neurodegeneration (BPAN), Kufor-Rakeb Syndrome, mitochondrial-membrane protein-associated neurodegeneration (MPAN), neuroferritinopathy, and PLA2G6-associated neurodegeneration (PLAN). This evidence concerns the gene PANK1 and neurodegeneration with brain iron accumulation 4.