In sum, these IHC/IF results confirmed the leukocyte infiltration patterns quantified by CIBERSORT, namely that cHL contain more CD3+ and CD4+ T-cell infiltrates than DLBCL, yet share high rates of CD8+ T-cells with non-GCB DLBCL and low rates of CD68+CD163+ TAM with GCB DLBCL. This evidence concerns the gene CD8A and classic Hodgkin lymphoma.