Expression of PD-1/PD-L1 in classical Hodgkin’s lymphoma (cHL) and in subtypes of diffuse large B-cell lymphoma patients (DLBCL) have been correlated with genetic alterations to the PD-L1 and PD-L2 locus of chromosome 9p24.1 (gains, amplifications, or fusions) [9,11,12,16,17]. Here, PDCD1LG2 is linked to diffuse large B-cell lymphoma.