IL2 and neuroblastoma: Of 13 patients with measurable soft tissue neuroblastoma tumors treated with Hu14.18-IL-2, no objective responses were seen, but in those with only MIBG-avid disease or with disease limited to the bone marrow, there were 5 complete responses out of 23 patients [126], suggesting that patients with minimal residual disease are most likely to benefit from this therapy.