Additional studies demonstrated significant efficacy of the mouse anti-GD2 antibody 3F8 in children with relapsed neuroblastoma, with 33% 5-year progression-free survival (PFS) in patients who were treated for relapsed neuroblastoma and achieved either a CR or very good partial response (VGPR) and were then treated with 3F8 plus GM-CSF and 13-cis-retinoic acid [10]. The gene discussed is CSF2; the disease is neuroblastoma.