IFNAR1 and Zika virus infectious disease: For vertical transmission studies, two models were developed: WT C57BL/6 females were crossed to WT C57BL/6 sires, and then dams were given the anti-Ifnar1 antibody immediately before ZIKV infection; or Ifnar1−/− dams were crossed to WT sires and then inoculated with ZIKV.