None of these theories would fully explain the outcome of the reported patient, having had a peculiar evolution as it presented as microcytic chronic anemia of unknown origin 14 years after open prosthetic incisional hernia repair, without evidence of chronic infection (thrombocytosis, elevated CRP), blind loop with breath testing or short gut with other markers of malnutrition. The gene discussed is CRP; the disease is thrombocytosis disease.