MUC5AC and colitis: Comparison of sequences at species level showed that relative abundance of mucin-degrading bacterium A. muciniphila belonging to the Verrucomicrobia phyla [36] was elevated in the CR+DBZ mice than either uninfected or CR-infected mice (Data not shown) that coincided with mucus layer disruption as was shown by us previously [16], suggesting that mucus degradation may precede onset of colitis in CR+DBZ-treated mice.