Co-localization of AsPC-1 exosomal ICAM-1 with macrophage CD11c suggests that uptake of AsPC-1 exosomes occurs via protein-mediated exosome-docking at the macrophage cell surface, and ICAM-1 could also promote cancer cell exosome uptake by other CD11c+ immune cells in the TME or at metastatic sites [35]. Here, ITGAX is linked to cancer.