SDC1 and Miyoshi myopathy: Previous studies have suggested that these CD138- cells were the MM CSC population, and we analyzed these pure, sorted populations to further characterize “stemness” by assessing: cell cycle phase (Fig 1C), long-term self-renewal/clonogenic potential (Fig 1D, 1E, 1G and 1H), chemoresistance (Fig 1F) and expression of differentiation specific markers (Fig 1I and 1J).