As shown in Table 2, using a cut-off value of 26 mm resulted in a significant association between invasive tumor size and NSLN metastasis (P <.001), but there was no significant association between non-SLN metastasis and age, histological type, tumor location, menstruation, venous involvement, molecular subtype, ER and/or PR status, or Ki-67 labeling index. The gene discussed is ESR1; the disease is neoplasm.