In this study, we proposed 5 mRNAs and 1 microRNA (INTS8, GTPBP2, ANK3, SLC16A12, LIMCH1, and hsa-mir-374a) as robust gene signature model that could effectively predict the prognosis for ccRCC. The gene discussed is SLC16A12; the disease is nonpapillary renal cell carcinoma.