TSPAN1 and adenocarcinoma: Wollscheid et al. evaluated TSPAN1 mRNA levels by RT-PCR and TSPAN1 protein levels by immunohistochemistry in cervical cancer and found that the gene was expressed in grade III cervical intraepithelial neoplasia, cervical squamous cell carcinoma, and adenocarcinoma, particularly in all undifferentiated cervical carcinomas and adenocarcinomas [31].