In the early days of using 68Ga-PSMA PET/CT, when the tracer was considered specific for prostate cancer, pitfalls in the interpretation of 68Ga-PSMA PET/CT studies were described, most of them as case reports [5, 17, 18, 20, 21], as well as case reports of 68Ga-PSMA avidity in other tumors (9–15). The gene discussed is FOLH1; the disease is Familial prostate cancer.