Five putative targets of ZJW (interleukin-6[IL-6], IL-1β, tumor necrosis factor [TNF]-α, monocyte chemotactic protein [MCP]-1 and EGFR), and two known therapeutic targets of gastritis (cholecystokinin-B receptors[CCKBR] and IL-12β) and a link target between ZJW and disease NF-κB are shown to be the most active factors that participate in these key pathways, which are implied an important role in the occurrence and promotion of gastritis. This evidence concerns the gene CCL2 and gastritis.