TXNDC9 and hepatocellular carcinoma: We performed immunohistochemical staining of TMAs containing 208 paired samples of HCC and normal liver tissues, and observed that the frequency of TXNDC9-positive staining in cancerous tissues (70.7%, 147/208) was statistically significantly higher than that observed in normal liver tissues (28.8%, 60/208) (p < 0.001, Fig. 1a).