AAAS and Triple A syndrome: Triple A syndrome, also known as achalasia‐addisonianism‐alacrima (triple A) syndrome (OMIM 231550), is a rare autosomal recessive disorder, caused by mutations in the AAAS gene (Handschug et al., 2001; Tullio‐Pelet et al., 2000; Weber et al., 1996).