The human homolog of Cbf1, USF1, has been associated with lipid biogenesis and hyperlipidemia in many studies (Auer et al., 2012; Coon et al., 2005; Di Taranto et al., 2015; Holzapfel et al., 2008; Huertas-Vazquez et al., 2005; Komulainen et al., 2006; Laurila et al., 2016; Lee et al., 2007; Meex et al., 2008; Naukkarinen et al., 2006; Naukkarinen et al., 2005; Naukkarinen et al., 2009; Ng et al., 2005; Pajukanta et al., 2004; Plaisier et al., 2009; Reiner et al., 2007; van der Vleuten et al., 2007). This evidence concerns the gene RBPJ and hyperlipidemia.