It is associated to histological type (p = 0.00173) and NOTCH1 is overexpressed in 73.2% of colon adenocarcinoma, 59.7% of colon mucinous adenocarcinoma, 84.4% of rectal adenocarcinoma and 76.9% of rectal mucinous adenocarcinoma. This evidence concerns the gene NOTCH1 and rectum mucinous adenocarcinoma.