For example, Limpitikul et al. reprogrammed dermal fibroblasts into iPSC-derived cardiomyocytes, then they used these cardiomyocytes to model calm2-associated Long-QT syndrome, which is a congenital birth defect associated with a mutation in the calcium binding protein calmodulin2, calm2 gene. The gene discussed is CALM2; the disease is Prolonged QT interval.