The IPA shows that the salubrinal-up-regulated genes tribbles-related protein 3 (TRB3), heme oxygenase 1 (HO-1), phosphoenolpyruvate carboxykinase (PCK2), and xCT might be involved in tumour cell survival, cell proliferation, and cell death (Supplementray Table S2). The gene discussed is HMOX1; the disease is neoplasm.