The data in Figure 2 show that the inhibition of constitutively expressed HIF1α and HIF2α in RC2 and 786.0 Clear-cell RCC cells, and HIF1α in FaDu head and neck [32], A548 lung carcinoma cells, and HT29 colorectal tumor cells is selenium dose-dependent and independent of the disease site/cell type. The gene discussed is EPAS1; the disease is lung carcinoma.