ANPEP, also known as CD13, is one of the enzymes that participate in the final digestion of peptides coming from the gastric hydrolysis of proteins [42] and participates in the rennin-angiotensin system that regulates vasopressin release, thus regulating arterial blood pressure and the pathogenesis of hypertension [43]. The gene discussed is ANPEP; the disease is Hypertension.