Though not in the list of 200 definite MS-associated SNPs, variants in NINJ2 have been identified as “suggestive” MS-associated SNPs.[6] The increased methylation in this gene in CD4+ T cells from MS cases could be due to NINJ2 variants, to an environmental factor, or to both, possibly acting in concert within an individual. Here, NINJ2 is linked to myeloid sarcoma.