It is interesting to note that although the secretory subtype is a squamous cell carcinoma subtype, it shows intermediate scores in the Adenocarcinoma factor (Fig 7B.2 and 7B.3, and S10 Fig), which is consistent with the fact that NKX2-1 is expressed in both the Secretory subtype and in adenocarcinomas. Here, NKX2-1 is linked to squamous cell carcinoma.