FOXP3 protein is a number of forkhead/winged helix families and has been recovered to function as suppresser of many cancers.15, 16, 17 Mir‐198 is a 22 bases RNA which regulates many proteins expression by interfering their translation.6, 18, 19, 20 But there are few reports on their cooperation for liver neoplasm. Here, FOXP3 is linked to liver neoplasm.