For forward research the effects caused by miR‐198 expression on MYC and liver neoplasm cells, we transfected miR‐198 mimics, miR‐198 inhibitor, pcDNA3.1‐MYC, and pcDNA3.1‐FOXP3 into HepG2 cells and they were divided into 6 groups: NC group, miR‐198 mimics group, miR‐198 inhibitor group, pcDNA‐MYC group, miR‐198 inhibitor+pcDNA‐FOXP3 group, and miR‐198 mimics+pcDNA‐MYC group. The gene discussed is FOXP3; the disease is liver neoplasm.