Plenty evidence has shown that MYC plays a vital role in liver neoplasm proliferation and hepatocarcinogenesis.11 A number of microRNAs that related to MYC have been figured out, for example, miR‐203 for cutaneous squamous cell carcinoma 12 and especially, miR‐122,13 miR‐206,4 and miR‐214 14 for liver neoplasm. Here, MYC is linked to cutaneous squamous cell carcinoma.