In order to understand whether CTLA4 is expressed in NSCLC, whether tumour cell‐intrinsic CTLA4 plays a role in tumorigenesis, we examined the CTLA4, PD‐1, PD‐L1 expression levels in multiple NSCLC cell lines with different oncogenic mutations and in the tissue samples from NSCLC patients. The gene discussed is CD274; the disease is neoplasm.