On day 28, the IL‐17A‐/‐+BLM+HSV1 mice had significantly lower IL‐12/23p40, KC, IL‐6 and G‐CSF compared with the WT+BLM+HSV1 mice, indicating that IL‐17A may contribute to the HSV1‐induced acute inflammation in fibrotic lung. Here, CALCA is linked to Bloom syndrome.