The same set of genes was found significantly upregulated in the DLPFC of the subgroup of MDD patients with psychotic characteristics compared to control subjects: HDAC4, HDAC5, HDAC6, HDAC8, and DNMT3B (by 83, 46, 83, 66, and 40%, respectively; p < 0.05). The gene discussed is HDAC4; the disease is major depressive disorder.