At the time of study enrolment, 93.7% of the participants were on a first-line NNRTI-based regimen, 77.8% (273/351) had advanced HIV infection (CD4 < 100 cells/ml) and the mean duration on ART was 75.5 months (95% CI: 69.0–81.9). The gene discussed is CD4; the disease is HIV infectious disease.