APOE and myeloid sarcoma: 31 Another investigation noted that the G allele of the IL6 SNP rs1800795 gene was associated with increased probability of MS and that the plasma fatty acid profile interacts with variants of the IL1B and IL10 genes to modulate manifestation of MS. 32 Another study with the ApoE polymorphism, involved in regulation of cholesterol and triglycerides metabolism found an association between the ApoE gene and the syndrome. 33