PRRT1 is part of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) complex, which is involved in glutamate transport in the central nervous system and is important for synaptic transmission.33,34 No mutations were found in the HLA class I and class II pathways in this patient’s tumour. This evidence concerns the gene PRRT1 and neoplasm.