In addition, we checked ERO1α expression in L02 normal liver cell line and five human HCC cell lines including HepG2, Hep3B, SMMC-7721, MHCC-97H, and Huh-7, and found significantly increased ERO1α mRNA levels in HCC cell lines (Fig. 1d). The gene discussed is ERO1A; the disease is hepatocellular carcinoma.