Several studies have demonstrated that TIM-3 polymorphism could be associated with ADs, such as multiple sclerosis (MS), Graves’ disease (GD), Hashimoto’s disease (HD), autoimmune thyroid diseases (AITDs), ankylosing spondylitis (AS), idiopathic thrombocytopenic purpura (ITP), systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) [21–32]. This evidence concerns the gene HAVCR2 and autoimmune thrombocytopenic purpura.