BMAL1 and cancer: With the use of novel genome editing methods, we thought that we can form a platform to study the effect of Bmal1 gene deletion at cellular and mechanistic level which may help us with investigating the relationship between Bmal1 gene disruption and the steps of multifactorial and multistage events in cancer development using non-tumorigenic MCF10A and invasive tumorigenic MDA-MB-231 cell lines.