To test the efficacy of combined models, we generated ATAC-seq data in EndoC-βH1 beta cells, an important cell line for studying T2D, and tested PEAS’s efficacy to predict enhancers in EndoC-βH1 cells in addition to enhancers in naïve CD8+ T cells, MCF7 and K562 cell lines (Fig. 1, step 3). Here, CD8A is linked to type 2 diabetes mellitus.